Serena Williams: Successful Weight Loss Taking Zepbound

For some patients using GLP-1s for medical weight loss, sharing their experience may be intimidating or something they want to keep private all together. Celebrities’ bodies are constantly under scrutiny in the media, including world famous tennis pro Serena Williams, 23-time Grand Slam champion.

Williams’s weight has been scrutinized her entire life. Even in her HBO documentary, “Being Serena,” one scene shows her coach talking with her about the need for her to lose weight.

Today, she is a champion of medical weight loss drugs. Williams announced publicly that she began taking Zepbound (tirzepatide, a dual GLP-1/GIP receptor agonist) in January 2025.

Despite a rigorous exercise regimen of walking 30,000 steps/day, strength training, and a specialized nutrition program for weight loss, she was unable to lose weight after her second child was born in 2023. In articles featured in both Elle and Vogue magazines, Serena Williams discussed motherhood, redefining diet culture, and GLP-1s. 

What Are the Results for Serena using Zepbound for weight loss?

Williams stresses that Zepbound is a tool for accelerating weight loss, not a shortcut. In conjunction with continuing a consistent diet and exercise routine, she lost 31 pounds. Instead of solely concentrating on the numbers on the scale, she focused on joint health, energy, and overall wellness according to an article in Women’s Health.

Zepbound is approved for the treatment of obesity or patients who are overweight and have weight related conditions such as high blood pressure, type 2 diabetes, and sleep apnea. The medication works best when combined with a healthy lifestyle, just like other GLP-1 medications.

Zepbound’s Bragging Rights

Cited in the New England Journal of Medicine, in a study comparing Zepbound to Wegovy for obesity management, the results declared Zepbound the superior medication.  After 72 weeks, the patients taking Zepbound (tirzepatide) lost almost 50% more weight than the patients taking Wegovy (semaglutide) or a placebo. Depending on the patient’s lifestyle, tirzepatide may be recommended for long-term use to prevent weight gain.

To determine which medical weight loss medication is right for you, contact Dr. Korman's office today or call 310-577-5540